Antonio de Nebrija University is a private and independent university which takes its name from the 15th century humanist who published the first grammar of the Spanish language. In keeping with the effort to expand Spanish language and culture and to promote understanding between people of many nations, the university welcomes students from all over the world to experience modern Spain in a traditional university setting. The university aspires to maintain the highest quality of scientific investigation and academic instruction. It is a small university, with an annual enrollment of approximately 3,000 Spanish students and 500 international students. The student to teacher ratio is roughly 10:1.

The university is divided into two campuses: Dehesa de la Villa and Berzosa. ISA students will take classes at the Dehesa de la Villa campus, which is conveniently located in northwest Madrid. It is well-communicated by metro and bus to the rest of the city. The Dehesa de la Villa campus is home to international students taking classes at the Hispanic Studies Center and also to Spanish students taking classes in Industrial Engineering and Computer Science Engineering. All of these students, international and Spanish alike, share the same academic building and have access to the same library, computer lab, cafeteria, and general university services.