System Pharmacology

Kingston University

Course Description

  • Course Name

    System Pharmacology

  • Host University

    Kingston University

  • Location

    London, England

  • Area of Study

    Biomedical Sciences, Life Sciences, Microbiology

  • Language Level

    Taught In English

  • Prerequisites

    Successful completion of introductory university level pharmacology such as LS5003 or
    similar.

  • Course Level Recommendations

    Upper

    ISA offers course level recommendations in an effort to facilitate the determination of course levels by credential evaluators.We advice each institution to have their own credentials evaluator make the final decision regrading course levels.

    Hours & Credits

  • Credits

    4
  • Recommended U.S. Semester Credits
    4
  • Recommended U.S. Quarter Units
    0
  • Overview

    Course Content:

    The module complements concepts delivered in Principles of Pharmacology with
    Research Methods (LS5003) and applies them to a number of physiological system
    disorders. The main feature of this module is, in each case, to study and discuss the
    disease pathophysiology and the types of drugs used in therapy of such disorders,
    alongside a rationale for their usage and any associated side effects.

    Autumn semester content summary: study of the major disease states associated with
    the cardiovascular, respiratory, renal and gastrointestinal, systems and drugs used to
    treat them.

    Spring semester content summary: study of the major disease states associated with
    the endocrine and nervous systems and drugs used to treat them.

    Topics covered may include:
    ? Mediator Pharmacology: Role of chemical mediators in the inflammatory
    response. Anti-histamines and treatment of allergic disease. Drugs affecting
    eicosanoid action including non-steroidal anti-inflammatory drugs i.e. cyclooxygenase
    (COX-1 and COX-2) inhibitors, 5-lipoxygenase inhibitors 5-FLAP
    inhibitors and leukotriene receptor antagonists. Platelet activating factor
    antagonists.
    ? Cardiovascular Pharmacology: vasodilators, diuretics and inotropic agents in the
    treatment of congestive heart failure with an emphasis on new therapies for
    heart failure e.g. adrenoceptor blockers, ACE inhibitors, neutral endopeptidase
    inhibitors, angiotensin II type I receptor blockers, vasopeptidase inhibitors,
    endothelin receptor antagonists, aldosterone receptor antagonists.
    ? Drugs used in the treatment of arrhythmias which include sodium channel
    blockers, adrenoceptor blockers, potassium channel blockers, calcium channel
    blockers and other anti-arrhythmic agents. Use of drugs for the treatment of
    angina, organic nitrates, adrenoceptor blockers and calcium channel blockers.
    Antihypertensive drugs, to include diuretics, ACE inhibitors, angiotensin II type I
    receptor blockers and, ?-adrenoceptor blockers. Drugs affecting blood, for
    example thrombolytics, lipid lowering agents and anti-coagulants.
    ? Respiratory Pharmacology: drugs used in the treatment of asthma which
    includes ?-adrenergic agonists, corticosteroids and other agents such as
    theophylline. Use of drugs to treat and manage chronic obstructive pulmonary
    diseases e.g. corticosteroids and ?-adrenergic agonists. Treatment of other
    respiratory disorders such as rhinitis and cough
    ? Renal and Urogential Pharmacology: Description of agents which cause
    natriuresis and diuresis. Drugs to be studied include loop diuretics, thiazide
    diuretics, potassium sparing diuretics, osmotic diuretics and carbonic anhydrase
    inhibitors. Drugs acting on urogenital smooth muscle which are used in the
    treatment of benign prostatic hypertrophy, impotency and overactive bladder
    ? Gastrointestinal Pharmacology: treatment of peptic ulcers with antimicrobial
    agents, histamine H2 receptor blockers, prostaglandins and proton pump
    inhibitors as well as more recent developments in the study of Helicobacter
    pylori. Therapies for other medical conditions involving the GI tract to include
    agents to combat diarrhoea and constipation as well as control of chemotherapyinduced
    emesis, Crohn?s disease and ulcerative colitis.
    ? Endocrine pharmacology: anti diabetic drugs, drugs acting on the thyroid,
    corticosteroids, sex hormones and their analogues.
    ? Neuropharmacology: autonomic pharmacology, introduction to techniques
    relevant to the study of neuropharmacology, anti Parkinsonian drugs,
    antidepressants, antipsychotics, anticonvulsants, hypnotics and sedatives, drugs
    of dependence and abuse.

    Teaching: Lectures, tutorials, workshops, presentation sessions and practical sessions

    Assessment:
    STUDY OPTION 1:
    ? Exam: MCQ and essay (60%)
    ? Practical: Presentation (20%) and practical assessment (20%)
    STUDY OPTION 2 or 3:
    ? Practical report (50%)
    ? Presentation (50%)

    Study Option 1 = Whole Year
    Study Option 2 = Autumn
    Study Option 3 = Spring/summer

Course Disclaimer

Courses and course hours of instruction are subject to change.

Eligibility for courses may be subject to a placement exam and/or pre-requisites.

Some courses may require additional fees.

Credits earned vary according to the policies of the students' home institutions. According to ISA policy and possible visa requirements, students must maintain full-time enrollment status, as determined by their home institutions, for the duration of the program.

Please reference fall and spring course lists as not all courses are taught during both semesters.

Please note that some courses with locals have recommended prerequisite courses. It is the student's responsibility to consult any recommended prerequisites prior to enrolling in their course.