From Quantum to Molecule
Vrije Universiteit Amsterdam
Amsterdam, The Netherlands
Area of Study
Taught In English
Physics, Medical Physics, Thermodynamics, Calculus, Mathematical Methods
Course Level Recommendations
ISA offers course level recommendations in an effort to facilitate the determination of course levels by credential evaluators.We advice each institution to have their own credentials evaluator make the final decision regrading course levels.
Recommended U.S. Semester Credits3
Recommended U.S. Quarter Units4
Hours & Credits
The overall aim of this course is to introduce the students to the basic mathematical language required to describe atoms, electrons, and
molecules by means of the quantum mechanical description of matter. On the one hand, the topics covered in the course are required to gain a better understanding of the physical basis of important chemical properties and physical reactions that appear frequently in a medical context. On the other hand, this formalism also allows us to translate quantum mechanical concepts into measurable quantities that can then be used for medical applications, such as positron therapy or magnetic nuclear resonance. In this course, we will therefore cover a number of topics which range from fundamental quantum mechanics to the corresponding applications in medical sciences.
The contents of the course are the following:
- It starts with a introduction to the quantum world, relevant for the description of small objects like atoms, molecules, and electrons. This
involves presenting important concepts such as the wave-particle duality, the De Broglie relations, and the Heisenberg uncertainty
principle of quantum mechanics.
- We will then move to present the fundamental equation of motion of quantum theory, namely the Schroedinger equation, and apply it to a
number of important systems such as the particle in a box, the hydrogen atom, the harmonic oscillator, and the hydrogen atom.
- The course will then explore next how quantum theory allows describing the binding mechanisms between atoms that lead to the formation of molecules. In this context, we will study the valence bond theory, the molecular orbital theory, the concepts of hybridization in molecular interactions, hydrogen bridges, and then Huckel theory for the description of pi-bonds in polyatomic molecules.
- In the last part of the course we will consider the phenomena associated to light-matter interactions in molecules, known as molecular
spectroscopy. We study vibrational modes in molecules, and how we can characterise them, as well as the mechanism underlying phosphorescence and photoluminescence. We emphasise their medical applications, such as Photosensitive Therapy and Magnetic Nuclear Resonance.
TYPE OF ASSESSMENT
Partial (midterm) and Final Exam, as well as short assessments (mini-test)
Courses and course hours of instruction are subject to change.
Some courses may require additional fees.