Molecular Biology of the Cell

Course Content:

The module builds on topics covered in LS4001 (Genes, Cells and Tissues) and explores
more advanced concepts in cell and molecular biology.

The module provides insight into the structure and functions of cells, and takes an
integrated approach to looking at how cells respond to changes in their environment ?
from receptor interactions and intracellular signalling pathways through to the regulation
of gene expression and changes in cellular processes.

Autumn Semester summary: cell biology and intracellular signalling.
? an overview of cellular and molecular processes in the cell
? cell structure, adhesion and motility
? intracellular trafficking and molecular motors
? cell cycle and cell death
? an introduction to receptor activation and intracellular signalling pathways.
? DNA packaging, chromatin modification and epigenetic regulation

Spring semester summary: molecular genetics
? DNA replication, transcription, translation and the regulation of gene expression
? mutation and the genetic code
? drugs that interfere with genetic processes
? practical methods relevant to cell and molecular biology, for example
fluorescence microscopy, RT-PCR
? data analysis and interpretation relevant to topics covered throughout the
module.

Teaching: Lectures, tutorials, workshops and practical sessions/demonstrations

Assessment:
STUDY OPTION 1:
? Exam (50%)
? Practical: In-course test of practical techniques and data-handling (25%) and a
group poster presentation (25%)
STUDY OPTION 2:
? poster assessment (50%)
? essay (50%)
STUDY OPTION 3:
? data-handling assessment (50%)
? essay (50%)

Study Option 1 = Whole Year
Study Option 2 = Autumn
Study Option 3 = Spring/summer