Introduction to Molecular Biology

DESCRIPTION:
Principles and applications of molecular biology, with emphasis on recombinant DNA technology, gene isolation and cloning, gene transfer into mammalian cells, transgenic animals, regulation of gene expression, molecular diagnostics, molecular biology of cancer and gene therapy.

RATIONALE: 
This course examines the fundamental molecular mechanisms controlling cellular functions. New genetic technology regarding gene manipulation and cloning will be extensively described along with its possible applications. The course aims at providing the student with a knowledge and understanding of recent advances in molecular biology and genetics.

LEARNING OUTCOMES: 
As a result of taking this course, the student should be able to:
1.Define the roles of genes in cell activity. (Knowledge)
2.Describe the regulatory control of gene expression. (Knowledge, Analysis, Evaluation)
3.Describe the importance of DNA manipulation and genes isolation. (Knowledge, Analysis, Evaluation)
4.Recognize the significance of gene transfer in mammalian cells. (Knowledge, Analysis, Evaluation, Application)
5.Interpret the molecular basis and origin of cancer. (Knowledge, Analysis, Evaluation)
6.Evaluate the power of gene therapy in modern medicine. (Evaluation, Application)
7. Develop the necessary analytical tools to understand the nature of scientific inquiry by practicing inquiry in the laboratory and by addressing the right questions and applying the appropriate methodology. (Key transferable skills, Practical skills)
(BI 1002) -2-

METHOD OF TEACHING AND LEARNING: 
In congruence with the learning and teaching strategy of the college, the following tools are used:
- Class lectures, interactive learning (class discussions, group work) video presentations, and practical problems solved in class.
- Exercises and primary source documents are assigned as homework, the solutions of which are reviewed in class
- Laboratory work (some laboratory reports and drawings may be required).
- CD-ROMS (Explorations in Cell Biology & Genetics).
- http://www.blackwellpublishing.com/Allison
- Office hours: students are encouraged to make full use of the office hours of their instructor, where they can ask questions, see their exam paper, and/or go over lecture/lab material.
- Use of a blackboard site, where instructors post lecture notes, assignment instructions, timely announcements, as well as additional resource