Pathophysiology of Heart and Circulatory System

Vrije Universiteit Amsterdam

Course Description

  • Course Name

    Pathophysiology of Heart and Circulatory System

  • Host University

    Vrije Universiteit Amsterdam

  • Location

    Amsterdam, The Netherlands

  • Area of Study


  • Language Level

    Taught In English

  • Course Level Recommendations


    ISA offers course level recommendations in an effort to facilitate the determination of course levels by credential evaluators.We advice each institution to have their own credentials evaluator make the final decision regrading course levels.

    Hours & Credits

  • ECTS Credits

  • Recommended U.S. Semester Credits
  • Recommended U.S. Quarter Units
  • Overview

    The aim of this course is to provide students with insight into the
    functioning of the cardiovascular system, the pathogenesis of the major cardiovascular diseases and in the possibilities for therapeutic intervention. Pathomechanisms are discussed that that can lead to the development of myocardial infarction and heart failure, mechanisms of genetic heart disease and the role of co-morbidities in cardiac disease.

    The course consists of the following subjects:
    - Macrocirculation and atherosclerosis
    - Microcirculation and vasoregulation
    - Heart function and myocardial infarction
    - Cardiomyopathies
    - Angiogenesis and arteriogenesis

    In the first part of the course, the properties of macrocirculation (atherosclerosis) and microcirculation (organ level) and their
    regulation are discussed, and the changes in the vessel wall that may lead to increased blood pressure and atherosclerosis.
    In the second part, the heart's action on molecule, cell and and organ level are discussed, the abnormalities (pathomechanisms) that
    arise and different forms of acquired and inherited cardiac disease.
    In the third part, the regulation of the barrier function of blood vessels is discussed and the role of angiogenesis and arteriogenesis.

    Lectures: 18 hours
    Practical courses: 6 hours
    Workgroups: 10 hours

    Report of research proposal & presentation: 20%, Exam: 80%. The two components of the test can be compensated and together they must be sufficient ( a grade of at least 5.5).


    Sufficient and demonstrable knowledge of the physiology and anatomy of the cardiovascular and respiratory system

Course Disclaimer

Courses and course hours of instruction are subject to change.

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